Affiliate Disclosure. This post is part of multi-part series shedding light on the latest treatments for common chronic conditions faced by an increasing number of Americans. In fact, if you are a man who would like to avoid getting cancer, the prostate is an excellent place to begin.
Approximately one in seven men will be diagnosed with prostate cancer at some point in their lifetime, and prostate cancer currently ranks as the third leading Prostatitis US of cancer death for men behind only lung and colorectal cancer. Although this is a post about prostate inflammation and not prostate cancer, the principal is the same: men need to take care of their prostates from a relatively early age.
And while the vast majority of the research dollars go to prostate cancer, prostatitis, or chronic inflammation of the prostate, is often lost in the shuffle. As such, this post will offer a series of easy experiments men can perform at home to either better protect, Prostatitis US heal the prostate. For example, the PH of urine can dictate whether bacteria like E. Similarly, the state of our dental hygiene also plays a role in the pathogenic load placed on the body.
The issue first came on my radar when visiting with a holistic dentist recently. He developed a product that raises the PH of the mouth Prostatitis US make it more alkaline. At first, I was skeptical seems everyone is selling a supplement todaybut then I did some reading.
In Prostatitis US, there Prostatitis US studies demonstrating significant improvement in prostate inflammation just by treating the gums alone. Yes, prostatitis can be contracted through sex, so the more sexual partners a man has, the higher his odds of developing Prostatitis US condition. Interestingly, Trichomonas vaginalisa Prostatitis US and STD, has been found in prostate biopsies of men with prostatitis, and although it seems that E.
M ineral deficiencies Prostatitis US common in the U. As far as food is concerned, pumpkin seeds and oysters are both high in zinc. Prostatitis can be contracted from sexual activity, but the very Prostatitis US used to treat prostatitis can, Prostatitis US some cases, be the culprit behind chronic inflammation of the prostate. The authors found that most young men presenting with prostatitis, who also had low prostate specific antigen PSA numbers higher Prostatitis US means greater likelihood of prostate cancerwere suffering from a yeast infection, not bacterial prostatitis, although E.
Bacterial Prostatitis US can raise PSA numbers, so if you have low PSA numbers, you may be looking at an anti-fungal regimen rather than a course of antibiotics. Broad-spectrum antibiotics, which is the solution offered by most urologists, will only serve to further destroy the microbial balance in the gut and urinary tract, making it that much easier for the yeast to spread. In these cases, loading up Prostatitis US antibiotics will only make matters worse.
An easy experiment to run if you suspect a fungal issue is to go Prostatitis US a type of Candida protocol for about 10 days and see how your body responds. In essence, this will involve eating zero sugar and following a low glycemic diet meaning very low carb but NOT zero carbs.
If these dietary changes provide relief, you have a decent idea that the problem is fungal in origin, especially if you have low PSA numbers. It is also a good idea to have a mycotoxin panel done to identify potential issues with toxic mold. The Central European Journal of Urology study used fluconazole, but some men may better tolerate nystatin. Prostatitis US would also note that the mechanistic justification for the low carbohydrate and anti-fungal diet in the Central European Journal of Urology could actually justify two experiments.
The one I list above is the anti-fungal-diet option very low carbwhich is proven in a well designed study, however, what seems to have been lost in that Prostatitis US is the suggestion that E.
Based on the studies I cite below in the plant based protocol section of this post, it could just as easily be argued that a diet, like many plant based protocols, that work to make the urine more alkaline could be just as effective, if Prostatitis US more so, at healing cases of prostatitis, since the rise in urine PH would remove the fuel source for E.
In the European study, the researchers gave the Prostatitis US potassium citrate to make their urine more alkaline. The prostate sits in an anatomical position, wrapped around the urethra, and close to the rectum, that is ripe for infection. Infection causes inflammation. Urine then gets trapped and backs Prostatitis US, which can contribute to lingering low grade infection, even where tests come back negative.
Leaky gut is characterized by bacteria, toxins, and even undigested food, which are all meant to stay within the digestive system, leaking out into the blood stream where these invaders have the potential to Prostatitis US autoimmune like reactions Prostatitis US some people. As a practical matter, this will overlap with the anti-fungal protocol above, but stop eating gluten for a month and see if Prostatitis US condition improves.
There Prostatitis US multiple anecdotal stories online about men healing prostate issues by cutting out gluten. And while the Paleo community has done an excellent job tagging grains as the cause of leaky gut, the reality is more complex for most men. Yes, grains, especially refined grains, can feed yeast and are contraindicated on an anti-fungal protocol, but some men will also do well to avoid saturated fat, as saturated fat has been linked to intestinal permeability as well.
The point here is that a low-grade Prostatitis US of the prostate can come from places you may not expect, including the gut. However, it is important to point out that many men have identifiable infection that can be detected through lab tests.
This quote from the Journal of Clinical Microbiology Reviews is instructive:. While it is difficult to Prostatitis US extrapolate from animal models, antibiotic pharmokinetic studies with a murine Prostatitis US have suggested that treatment failures in chronic prostatitis are probably a result of the Prostatitis US microenvironment surrounding the persistent focal and well-protected small bacterial biofilms buried within the prostate gland.
These conclusions support the molecular and culture data implicating bacteria as a cause Prostatitis US chronic idiopathic prostatitis. However, antibiotics Prostatitis US penetrate the prostate effectively. Forums are full of men who claim to have had some temporary relief from antibiotic use, only to have symptoms return when antibiotics stop.
Ironically, and as the studies on yeast infections above demonstrate, antibiotic use may be one of the primary contributing factors to long battles with prostatitis. To be fair, antibiotics may have efficacy for men suffering with an acute infection. However, for chronic repeat sufferers, antibiotics are not a cure, because, as the Journal of Clinical Prostatitis US states, bacteria can thrive in a prostate not receiving proper blood flow due to bacteria fortified Prostatitis US biofilm.
The popular erectile dysfunction drugs Cialis and Viagra Prostatitis US because they flood NO into the prostate region also relieving symptoms of BPH. NO Prostatitis US anti-pathogenicbut unfortunately, infection reduces BH4a chemical the body needs to make NO.
So, in essence, an infected prostate loses the ability to receive NO because the body uses BH4 to fight off the invaders, rather than to synthesize NO. Therefore, lingering infection means lower NO bioavailability, reduced blood flow, and greater risk for infection, or greater risk for lingering infection to better protect itself with production of biofilm.
Whether you want to call it acute bacterial, or chronic nonbacterial, prostatitis is a recurrent inflammation of the prostate caused in part by chronic decline in nitric oxide bioavailability. The recent literature suggests that the condition referred to as chronic idiopathic nonbacterial prostatitis may actually have an infectious etiology.
During the past few years, molecular data and cultures performed with special media discussed below strongly suggested that chronic idiopathic prostatitis may actually be a cryptic bacterial infection of the prostate gland that is usually missed or undetected by routine Prostatitis US cultures in clinical microbiology laboratories.
Decline in the anti-pathogenic NO results in poor blood flow to the prostate, which adds an anaerobic environment to a region that sits next to multiple potential sources of infection. The stage is then set for infection to settle in, with E. It is for this reason that studies have shown that use of the ED drug Cialis, actually helps heal and reduce inflammation markers in the prostate.
Flooding the region with NO, reduces cytokine Prostatitis US. In response to inflammation, the body produces a greater number of localized mast cells, which makes matters worse. Therefore, mast Prostatitis US production in the bladder and prostate is basically an allergic response to inflammation that can increase the inflammatory cycle and locally suppress the immune system.
After a long period of inflammation, which has caused mast cells to pool in the prostate area, seasonal allergies can contribute to symptoms. The mast cells are there in larger numbers and will release their inflammatory cocktail in greater concentrations in areas of the body that Prostatitis US perceived as under attack. If you Prostatitis US allergies, cutting out saturated fat and going on more of a plant based diet for awhile could be helpful, especially, as we will see when you pair with certain antihistamines.
Both quercetin and bromelain act as natural antihistamines, which Prostatitis US mast cell count and eases symptoms. This double blind, placebo controlled study found that quercetin and bromelain to be effective at treating prostatitis. Quercetin fits under the three prostate rules listed above both as a mast cell stabilizer and a biofilm disrupter. Prostatitis US interesting study from did highlight some potential markers and interestingly identified differential treatment responses based on genetics.
IL is a major anti-inflammatory cytokine, a protein released by cells which helps damp down the Prostatitis US response, and so a lack of its expression is therefore associated with chronic inflammatory disorders. Berberinewhich I have written about previously as an anti-cancer supplement, has been shown in some animal studies to cure prostatitis.
There is a community of functional medicine doctors, the most vocal being Dr. Dach in South Florida, who believe that berberine heals leaky gut. Healing of leaky gut, Prostatitis US by wiping out pathogenic bacteria, closes the doorway for bad bacteria to enter the blood stream and infect the prostate.
Berberine Prostatitis US anti-fungal and antimicrobial. It fits nicely within our three rules for prostate health listed above.
As an added benefit, berberine has been proven as a prostate healthy supplement in the context of prostate cancer where it inhibited growth of prostate cancer cells. To further advance this theory, this study in the Journal of Urology found that taking H1 antagonists, like Zyrtec or Claritin, helped alleviate prostatitis.
Just as the quercetin did, the antihistamine reduced mast cell count, thus dialing back inflammation. Men Prostatitis US chronic pelvic pain syndrome showed increased mast cell tryptase and nerve Prostatitis US factor in expressed prostatic secretions.
Treatment of experimental autoimmune prostatitis with a mast cell stabilizer combined with a histamine 1 receptor antagonist resulted in a synergistic decrease in chronic pelvic pain. This study out of the University of Washington in St. Louis found that people with more acidic Prostatitis US had greater likelihood of developing repeated urinary tract infections, especially those driven by Prostatitis US.
Now think back to the yeast study I quoted above. The authors there believe that E. Coli was the bridge that allowed Candida and other pathogenic yeast to infect the prostate.
The UTI Prostatitis US then spread to the prostate or bladder, causing chronic problems. In fact, the urinary tract has its own microbiome, and certain strains of probiotics may play a role Prostatitis US staving off infection.
High animal protein diets cause greater acidity in the urine which allows for the invasion of bad bacteria, like E. Colithat are linked to prostate inflammation. If too much animal protein causes acidity that proliferates E. Coliand eventually Candida, a plant based diet that makes the urine more alkaline could be a solution to prostate issues for some men. For more on how potassium citrate makes the urine more alkaline, see this Prostatitis US of Chicago article.
In this context, it is crucial to know your blood type. Although the blood type diet has largely been debunked, it contains one sound scientific principle, which is that blood type correlates to hydrochloric acid levels in the stomach. A high protein diet in these individuals may leave undigested meat fermenting in the gut, which leads to pathogens, like E. Coli, that can cause problems for the urinary tract and prostate. Last, red meat in particular has been shown to be a problem for those with mast cell issues.
If chronic inflammation, or some type of under the radar autoimmune condition, has caused a localized increase in mast cells or E.